Cycobalamin yog ib qho ntawm cov vitamin B complexes, uas muaj zog anti-pernicious anemia nyhuv. Nws yog lub npe muab los ntawm crystallization ntawm vitamin B12, qhov tseem ceeb tshaj plaws rau kev loj hlob ntawm cov kab mob thiab tsiaj txhu. Dhau li ntawm C, H, O, N, P thiab Co, aD-ribose conjugate ntawm 5,6-dimethe-rbenzimidazole yog ib feem ntawm nws cov qauv. AR Todd et al. muab tso rau pem hauv ntej cov qauv qauv, uas yog hu ua cyanocobalamin vim cyano yog kev sib koom tes ntawm cobalt. Qhov siab tshaj plaws nqus dej hauv cov kua dej yog 278,361,548 nm. Xyoo 1948, E.L.Rickes ntawm Tebchaws Meskas thiab E.L.Smith ntawm tebchaws United Kingdom ntawm nws tus kheej tau rho tawm cov muaju los ntawm daim siab. Txij thaum ntawd los, cov tshuaj no kuj tau txais los ntawm qee yam actinomycete (StrePtomyces griseum).Cyanocobalamin kuj yog qhov tseem ceeb ntawm kev loj hlob ntawm npua thiab qaib, thiab nws yog tib yam khoom raws li tsiaj protein yam tsim nyog rau qe hatching. Vitamin B12, muab rau cov neeg mob uas muaj kab mob malignant ntawm 150 micrograms, tuaj yeem ua rau cov ntshav liab nce li 2 zaug, thiab 3-6 micrograms tuaj yeem tsim cov teebmeem. Nyob rau hauv vivo, nws yog thauj nyob rau hauv cov ntshav nyob rau hauv daim ntawv ntawm kev sib xyaw nrog trans-cobalamin protein (a- globular protein), thiab muaj nyob rau hauv daim ntawv ntawm coenzyme nyob rau hauv ntau yam ntaub so ntswg. Ua ke nrog folic acid, nws muaj kev koom tes hauv cov metabolism ntawm methyl hloov thiab nquag methyl tiam. Thiab dhau los ua qhov tseem ceeb ntawm purine, pyrimidine thiab lwm yam biosynthesis.
